View abstract. Semin Oncol 1998;24:3-9. Yellowing of the skin in infants (neonatal jaundice). View abstract. Effect of intragastric pH on the absorption of oral zinc acetate and zinc oxide in young healthy volunteers. 2016;29(13):2194-8. Sayyah M, Olapour A, Saeedabad Ys, Yazdan Parast R, Malayeri A. Prema K, Ramalakshmi Ba, Babu S. Serum copper and zinc in hormonal contraceptive users. Failure of zinc gluconate in treatment of acute upper respiratory tract infections. Zinc metabolism in patients treated with captopril versus enalapril. King JC. Am.J.Clin.Nutr. Initial therapy in 33 neurologically affected patients and follow-up with zinc therapy. Efficacy of spirulina extract plus zinc in patients of chronic arsenic poisoning: a randomized placebo-controlled study. Complement Ther Clin Pract 2009;15(2):91-95. View abstract. J Lab Clin Med 1998;132:264-78. Sandstrom B, Almgren A, Kivisto B, Cederblad A. 2009;20(12):1000-1012. Zinc oxide is widely used in the manufacture of very many products such as paints, rubber, cosmetics, pharmaceuticals, plastics, inks, soaps, batteries, textiles and electrical equipment. Zinc supplementation as adjunct therapy in children with measles accompanies by pneumonia: a double-blind, randomized controlled trial. View abstract. Zinc and immunity. Tyrer LB. View abstract. Am J Clin Nutr 1984;39:535-9. Bahl, R., Bhandari, N., Saksena, M., Strand, T., Kumar, G. T., Bhan, M. K., and Sommerfelt, H. Efficacy of zinc-fortified oral rehydration solution in 6- to 35-month-old children with acute diarrhea. Gupta VL, Chaubey BS. Christian P, Khatry SK, Yamini S, et al. The in vivo effect of zinc on platelet membranes and cognition. Cornea 1996;15(6):582-588. Safety and efficacy of zinc supplementation for children with HIV-1 infection in South Africa: a randomised double-blind placebo-controlled trial. Arch Ophthalmol 1988;106:192-8. Pharmacol Toxicol 1989;65:209-13. 2013 Jul 18;122(3):311. Akhondzadeh S, Mohammadi MR, Khademi M. Zinc sulfate as an adjunct to methylphenidate for the treatment of attention deficit hyperactivity disorder in children :a double blind and randomized trial. Giving zinc to underweight infants in developing countries seems to decrease the risk of death, prevent certain complications, and improve mental ability. View abstract. Am J Epidemiol 1996;143:1244-56. AOX. Histopathologic findings regarding two patients. Nielsen FH, Milne DB. Humphreys, E. H., Smith, N. A., Azman, H., McLeod, D., and Rutherford, G. W. Prevention of diarrhoea in children with HIV infection or exposure to maternal HIV infection. The two main advantages that zinc-alkaline batteries have over other battery types is that they tend to resist leaking more, and they have longer shelf life. Shah GS, Dutta AK, Shah D, Mishra OP. Camacho FM, Garcia-Hernandez MJ. Bogden, J. D., Oleske, J. M., Lavenhar, M. A., Munves, E. M., Kemp, F. W., Bruening, K. S., Holding, K. J., Denny, T. N., Guarino, M. A., and Holland, B. K. Effects of one year of supplementation with zinc and other micronutrients on cellular immunity in the elderly. Int J Cancer 2005;116:182-6. Ewing CI, Gibbs AC, Ashcroft C, David TJ. 2016;12:CD005436. Yousefichaijan P, Naziri M, Taherahmadi H, Kahbazi M, Tabaei A. Zinc supplementation in treatment of children with urinary tract infection. Factors affecting zinc homeostasis. Effects of oral zinc and vitamin A in acne. View abstract. Lancet 2000;355:2021-6. Kugelmas M. Preliminary observation: oral zinc sulfate replacement is effective in treating muscle cramps in cirrhotic patients. Epidemiology 2002;13:38-44.. View abstract. Trace elements during 2 years' oral contraception with low-estrogen preparations. 2012;6:CD005436. Epilepsia 1982;23:453-61. View abstract. Sazawal, S., Jalla, S., Mazumder, S., Sinha, A., Black, R. E., and Bhan, M. K. Effect of zinc supplementation on cell-mediated immunity and lymphocyte subsets in preschool children. A double-blind trial of a zinc sulphate/citrate complex and tetracycline in the treatment of acne vulgaris. Zinc supplement use and risk of prostate cancer. Baltimore, MD: Williams & Wilkins, 1999. Fuller NJ, Bates CJ, Evans PH, Lucas A. Fleet JC, Turnbull AJ, Bourcier M, Wood RJ. Depression. Arch Androl 1981;7(1):69-73. View abstract. View abstract. Godfrey HR, Godfrey NJ, Godfrey JC, Riley D. A randomized clinical trial on the treatment of oral herpes with topical zinc oxide/glycine. View abstract. View abstract. Cancer of the white blood cells (leukemia). Eur J Clin Nutr. J Nutr 1989;119:48-53. Cisplatin (Platinol-AQ) interacts with ZINC. 2003;22(1):21-29. Effect of treatment with zinc gluconate or zinc acetate on experimental and natural colds. View abstract. Interaction with other anticopper agents. View abstract. 1990;10(1):63-69. Roy SK, Tomkins AM, Akramuzzaman SM, et al. View abstract. Castillo-Duran, C., Rodriguez, A., Venegas, G., Alvarez, P., and Icaza, G. Zinc supplementation and growth of infants born small for gestational age. View abstract. Anosmia due to inhalational zinc: a case report (abstract). 1993;69(1):243-255. Zinc metabolism during captopril treatment. Samman, S. and Roberts, D. C. The effect of zinc supplements on lipoproteins and copper status. View abstract. Mahajan SK, Prasad AS, Lambujon J, et al. Zavaleta N, Caulfield LE, Garcia T. Changes in iron status during pregnancy in peruvian women receiving prenatal iron and folic acid supplements with or without zinc. Some research suggests that taking zinc along with antidepressants improves depression in people with major depression. J Ren Nutr 2002;12(3):183-189. Clin Lab Med 1998;18:673-85. When you think of a penny does the image of a copper coin come to mind? Hurd RW, Van Rinsvelt HA, Wilder BJ, et al. View abstract. View abstract. A., Nizami, S. Q., and Isani, Z. Zinc supplementation in malnourished children with persistent diarrhea in Pakistan. Ann Intern Med 1996;125:81-8. Interaction of riboflavin with zinc bioavailability. BMJ 2-2-2008;336(7638):266-268. Lockitch, G., Puterman, M., Godolphin, W., Sheps, S., Tingle, A. J., and Quigley, G. Infection and immunity in Down syndrome: a trial of long-term low oral doses of zinc. 2003;23(1):3-8. To continue your studies on this topic, be sure to review the related lesson titled Zinc: Uses in Everyday Life, Industry & Medicine. Ranjbar E, Shams J, Sabetkasaei M, M-Shirazi M, Rashidkhani B, Mostafavi A, Bornak E, Nasrollahzadeh J. Moore, R. Bleeding gastric erosion after oral zinc sulphate. Cochrane Database Syst Rev 2010;(6):CD008563. Role in Your Body Zinc is a vital mineral that your body uses in countless ways. Zinc-air batteries are often used to make button cell batteries. Taking zinc sulfate by mouth might improve liver function in people with alcohol-related liver disease. Lawson KA, Wright ME, Subar A, et al. 2016;83(4):289-93. Zinc is found everywhere in daily life: in every cell of the human body, in the earth, in the food we eat and in products we use (sunblock, automobiles, cosmetics, airplanes, appliances, surgical tools, zinc lozenges… Lukacik, M., Thomas, R. L., and Aranda, J. V. A meta-analysis of the effects of oral zinc in the treatment of acute and persistent diarrhea. Davidsson L, Almgren A, Sandstrom B, Hurrell RF. J Dermatolog.Treat. Research shows that zinc is helpful in various health applications such as regulation of the immune system, acne reduction, and treatment of stomach ulcers. The Age-Related Eye Disease Study (AREDS) Research Group. View abstract. Pediatrics 2007;119:1120-30. Mahajan PM, Jadhav VH, Patki AH, et al. View abstract. Evaluation of zinc status in subjects with Crohn's disease. View abstract. Eur.J Clin Nutr. View abstract. A. Zinc supplementation for the prevention of pneumonia in children aged 2 months to 59 months. Some other medical uses and health applications of zinc are: • improvement of various learning and memory functions, • promotion of sufficient growth in children, • personal care products such as sunscreens, diaper rash ointments, toothpaste, and bath soap. WebMD does not provide medical advice, diagnosis or treatment. Lancet 9-17-2005;366(9490):999-1004. Treatment of Wilson disease with ammonium tetrathiomolybdate. Vitamin D-sensitive and quinacrine-sensitive zinc transport in human intestinal cell line Caco-2. You've been carrying around a bunch of pennies in your pocket, so you decide to use them to pay for some of the items. View abstract. Zinc might decrease how much antibiotic the body absorbs. Gynecol Obstet Invest 1988;25:113-7. Curr Ther Res 1998;59:595-607. Spinal bone loss in postmenopausal women supplemented with calcium and trace minerals. Role of zinc administration in prevention of childhood diarrhea and respiratory illnesses: a meta-analysis. Applying zinc to the skin in an ointment does not seem to help treat acne unless used in combination with the antibiotic drug called erythromycin. Br J Clin Pharmacol. Altunbasak S, Biatmakoui F, Baytok V, et al. Zinc and copper concentrations in leukocytes and erythrocytes in healthy adults and the effect of oral contraceptives. View abstract. Husain, S. L. Oral zinc sulphate in leg ulcers. Int J Eat Disord 1994;15:251-5. View abstract. 2013 Dec 15;74(12):872-8. Preterm birth. Low maternal vitamin E intake during pregnancy is associated with asthma in 5-year-old children. Taking zinc sulfate by mouth also appears to be effective. Farhang B, Grondin L. The Effect of Zinc Lozenge on Postoperative Sore Throat: A Prospective Randomized, Double-Blinded, Placebo-Controlled Study. View abstract. Dalgic, N., Sancar, M., Bayraktar, B., Pullu, M., and Hasim, O. Probiotic, zinc and lactose-free formula in children with rotavirus diarrhea: are they effective? Hebel SK, ed. Mills CF. A trial of oral zinc supplementation in psoriasis. View abstract. View abstract. Am.J.Ther. View abstract. View abstract. Int Dent J. View abstract. Br J Nutr 2008;99(3):667-673. Hypochlorhydria from short-term omeprazole treatment does not inhibit intestinal absorption of calcium, phosphorus, magnesium, or zinc from food in humans. Applying zinc sulfate or zinc oxide to the skin, alone or with other ingredients, seems to reduce the duration and severity of oral and genital herpes. View abstract. 2009;118(1-3):187-195. Taking zinc during pregnancy does not seem to reduce the risk of having a newborn with low birth weight. 1-1-2004;58(1):167-174. Schisterman EF, Sjaarda LA, Clemons T, et al. Arch Dermatol 1978;114:1018-20. View abstract. Int J Lepr Other Mycobact Dis 1984;52:331-8. Effect of zinc therapy on natural killer cell activity in inflammatory bowel disease. View abstract. Am J Clin Nutr 2000;72:1516-22. Drugs 1976;11:45-54.. View abstract. Johns Hopkins Med J 1975;136:137-44. Conditions in a man that prevent him from getting a woman pregnant within a year of trying to conceive (male infertility). Early research suggests that applying a zinc solution twice daily improves wound healing compared to applying a saline solution. Am.J.Med. Effect of omeprazole on plasma zinc levels after oral zinc administration. Liukko P, Erkkola R, Pakarinen P, et al. Cystic fibrosis. Palomo F, Wantland L, Sanchez A, Volpe AR, McCool J, DeVizio W. The effect of three commercially available dentifrices containing triclosan on supragingival plaque formation and gingivitis: a six month clinical study. Comparison of intralesionally injected zinc sulfate with meglumine antimoniate in the treatment of acute cutaneous leishmaniasis. Food and Nutrition Board, Institute of Medicine. Cancer Chemother Pharmacol 1992;29:219-26. 2008;(3):CD005436. Pinna A, Corda L, Carta F. Rapid recovery with oral zinc sulphate in deferoxamine-induced presumed optic neuropathy and hearing loss. Clin Nephrol 1982;17:254-7. 1986;13(4):301-306. Zinc Supplementation in Preterm Neonates and Neurological Development, A Randomized Controlled Trial. View abstract. Research suggests that applying an ointment containing zinc and aluminum to the anus three times daily for 4 weeks improves symptoms and quality of life in women with a loss of control of bowel movements. Zinc, biochemical markers of nutrition, and type I osteoporosis. Nutrients. Butterworth CE, Hatch K, Cole P, et al. Kingberg WG, Prasad AS, Oberleas D. Zinc deficiency following penicillamine therapy. Sprenger KB, Bundschu D, Lewis K, et al. Bianchi GP, Marchesini G, Brizi M, et al. Evaluation of oral zinc sulfate effect on obsessive-compulsive disorder: a randomized placebo-controlled clinical trial. A. View abstract. View abstract. Zinc as an adjunct therapy in the management of severe pneumonia among Gambian children: randomized controlled trial. View abstract. A., Qadri, S. S., Chowdhury, M. I., Saha, A., Larson, C. P., and Qadri, F. Zinc influences innate immune responses in children with enterotoxigenic Escherichia coli-induced diarrhea. Hyperzincuria and hypozincemia in patients treated with cisplatin. Glob Health 2018;8(1):010418. 1996;63(4):514-519. Cataracts. J Pediatr 1998;132:467-71. View abstract. Heart disease. View abstract. Fatemi SH, Calabrese JR. View abstract. Indian J Pathol Microbiol 1997;40:451-5. View abstract. Saxton, C. A., Harrap, G. J., and Lloyd, A. M. The effect of dentifrices containing zinc citrate on plaque growth and oral zinc levels. Am J Clin Nutr 2003;78:279-83.. View abstract. View abstract. Oral zinc sulphate in the treatment of acute cutaneous leishmaniasis. This lesson describes some of the ways that zinc is used in everyday life, industry, and in medicine. Cochrane Database Syst Rev 2000;(2):CD001364. Turner RB. Applying zinc oxide paste also seems to improve the healing of diaper rash. Pediatrics 1998;102(1 Pt 1):1-5. The influence of some antipsychotics on erythrocyte magnesium and plasma magnesium, calcium, copper and zinc in patients with paranoid schizophrenia. Research suggests that taking zinc sulfate improves behavior and social abilities in people with memory loss. Brandrup, F., Menne, T., Agren, M. S., Stromberg, H. E., Holst, R., and Frisen, M. A randomized trial of two occlusive dressings in the treatment of leg ulcers. Med Hypotheses 1993;40:182-5. 2014 Jun;121:17-8. Koehler, K., Parr, M. K., Geyer, H., Mester, J., and Schanzer, W. Serum testosterone and urinary excretion of steroid hormone metabolites after administration of a high-dose zinc supplement. J Rheumatol 1997;24:643-6. View abstract. 1982;41(5):456-457. Ann NY Acad Sci 1992;669:314-6. We could see more of such innovative products as more and more electronic and kitchenette items are developed. Zinc sulfate for relief of pruritus in patients on maintenance hemodialysis. The effects of thiazides on serum and urinary zinc in patients with renal calculi. View abstract. J Invest Dermatol 1986;86:715-6. View abstract. Metab Pediatr Syst Ophthalmol 1989;12:80-2. Cancer that starts in white blood cells (non-Hodgkin lymphoma). 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Activity in inflammatory bowel disease or IBD ) Karatzas N, Dincer N, Gopalakrishna SM year among with!